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GallCleanse ^TM  for Gall Stones
Clinical Studies & Doctor Recommendations

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Clinical Study Information

Below are detailed clinical references from independent scientific journals of the effectiveness of GallCleanse by Bioneutrix. For each specific effect, specific clinical proof is shown.

GallCleanse as a Stone Dissolvant
A breakthrough study¹ done by the Somerville and Ellis postgraduate research team conclusively showed how the monoterpene complex was able to dissolve gallstones effectively in the bile ducts. GallCleanse Dissolvent includes the monoterpenes camphene, menthol and menthone that have the proven stone dissolving effect.

 
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 30 day supply. Includes 1 bottle of Dissolvent formula and 1 bottle of Flush formula.

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An additional study² ³ by Holtz was able to verify that complete dissolution could be achieved in most gallstone cases with the use of this terpene complex.

1. Somerville KW, Ellis WR, Postgrad Med J. 1985;61:313-316
2. Holtz S: Nat Med 2(January): 6-19, 1999
3. Br Med J (Clin Res Ed). 1984 Jul 21;289(6438):153-

 
GallCleanse for Gallstone Pain Relief
In 2003, a research team headed by K.J Goerg and TH Spilker¹ showed that caraway oil when combined with peppermint oil - both found in GallCleanse Dissolvent - caused the gallbladder to relax. Relaxation of the gallbladder quickly eases the pain of sharp gallbladder attacks.

Another breakthrough study² showed how the turmeric root in GallCleanse Flush was an effective anti-inflammatory agent. It was shown to stimulate the anti-inflammatory mechanism similar to prescription phenylbutazone, but more safely.

1. Alimentary Pharmacology & Therapeutics Volume 17 Page 445 - February 2003 doi:10.1046/j.1365-2036.2003.01421.x Volume 17 Issue 3 K. J. Goerg & TH. Spilker
2. Luper S. A review of plants used in the treatment of liver disease: part two. Altern Med Rev 1999; 4 178-188

 
GallCleanse for Improving Gallbladder Function

The extract of Artemisia Argyi found in GallCleanse was shown¹ to help expel bile solids and gallstones. The Sun Yat-Sen University of Medical Sciences research team² concluded that this ingredient helped control gallbladder contractions by increasing the frequency of contracting and relaxing in a smoother manner.

An additional placebo controlled trial³ showed how another ingredient in GallCleanse, curcumin, had a positive contraction effect on the gallbladder -- allowing the gallbladder to better empty itself of potentially stone-forming bile.

1. Chin Med J (Engl). 1993 Feb;106(2):145-8. Ultrasonic studies of the effect of artemisia decoction on the volume and dynamics of gallbladder. Yu ZF, Wu XS. 
2. Department of Surgery, Third Affiliated Hospital, Sun Yat-Sen University of Medical Sciences, Guangzhou 
3. Aliment Pharmacol Ther. 1999 Feb;13(2):245-9.
    

GallCleanse for Improving Liver Function
Two separate teams independently confirmed the specific liver improving effects of Betaine in GallCleanse Flush. The first team¹ was able to show how this flush ingredient was able to reverse fatty infiltration in the liver. The second team² concluded that Betaine was able to protect the liver from toxins and reduce hepatotoxicity. Two additional research labs have validated specific liver improving function of ingredients in GallCleanse Flush: A team in Hungary³ noted how silymarin protected the liver under stress. Another team ⁴  was able to show how the same active ingredient also reversed sluggish liver function which is a major contributing factor to gallstone formation. 

1. Barak AJ, Beckenhauer HC, Junnila M, et al. Dietary betaine promotes generation of hepatic S-adenosylmethionine and protects the liver from ethanol-induced fatty infiltration. Alcohol Clin Exp Res. 1993;17:552–555
2. Kanbak G, Inal M, Baycu C. Ethanol-induced hepatotoxicity and protective effect of betaine. Cell Biochem Funct. 2001;19:281–285
3. Feher J, Desk G, Muzes G, et al. Liver protective action of silymarin therapy in chronic alcoholic liver diseases [in Hungarian]. Orv Hetil. 1989;130:2723–2727
4. Giannola C, Buogo F, Forestiere G, et al. A two-center study on the effects of silymarin in pregnant women and adult patients with so-called minor hepatic insufficiency. Clin Ther. 1985;114:129–135.

 
GallCleanse For Improving Bile Quality
Thick bile flows slower and has high levels of stone-forming cholesterol. Three independent studies were able to show how active ingredients in GallCleanse increase the flow and liquidity of bile.

The first study¹ documented how the chelidonium oil complex, found in GallCleanse Flush, was able to selectively increase bile flow.

The other two studies showed how curcumin increased the volume of bile sent to the liver. Doctors Ammon and Wahl² were able to show how curcumin increased bile production while Doctors Ramprasad and Sirsi³ confirmed this effect and also demonstrated that the bile produced was more diluted.

1. Vahlensieck U, Hahn R, Winterhoff H et al. Planta Med 1995; 61 (3): 267 – 271.
2. Ammon H.P., Wahl M.A. Pharmacology of Curcuma Longa; Planta Medica 1991; 57: 1-7
3. Ramprasad C., Sirsi M. Curcuma Longa and Bile secretion - quantitative changes in bile constituents induced by sodium curcuminate. J Sci Industr Res C1957; 16 108-110
    

GallCleanse For Preventing New Gallstones
The breakthrough of the GallCleanse formula is that it has a clinical basis for breaking the gallstone cycle and keeping new stones from forming. There are two mechanisms by which GallCleanse can prevent new stones:

• By reduction of total lipids and cholesterol in bile
• By reduction of the inflammatory process of the gallbladder that triggers stone formation

The National Research Center in Cairo¹ was able to conclude that one of the active constituents of GallCleanse, ginseng, was able to reduce total lipid and cholesterol secretion in bile.

It has been shown that gallbladder inflammation plays a major role in the gallstone cycle promoting more stone formations.

A 1996 study² concluded that the berberine alkaloids in the Oregon grape extract found in GallCleanse inhibit lypoxygenase which normally produces leukotrienes that cause inflammation in the gallbladder. This is remarkable evidence that supports GallCleanse's effectiveness in ending the cycle of gallstones.

1. Omar M. E. Abdel Salam1, Somaia A. Nada and Mahmoud S. Arbid Department of Pharmacology, National Research Centre, Dokki, Cairo, Egypt 25 February 2002.
2. Kam D.M., Webb P.A., Sandman G., Chug A., Vertz M.L., Scheeres D.E., A novel 5-lypoxygenase inhibitor prevents gallstone formation. Am Surg 1996; 62: 551-556

In addition to these independent trials, Bioneutrix labs is currently conducting it's very own efficacy study under WHO protocols in Asia.

Doctor Recommendations for GallCleanse (provided by BioNeutrix)

"As a physician with over 15 years of experience, I have treated hundreds of gallstone patients. In most cases I have noticed that the removal of the gallbladder could have been avoided through conservative therapies such as GallCleanse. Over the past year, I have been advising my patients to go on the GallCleanse therapy for 2 months. Almost all patients report an immediate reduction in painful symptoms and many who have screened for stones have been able to see pieces being flushed out during their therapy. I believe GallCleanse is at the forefront of natural gallstone therapy and offers a safer way to treat gallstones."
--Dr. M. Thomas, Internal Medicine

"To treat gallstones effectively, every patient has to treat the biliary root of the problem - poor gall bladder contractions and thick flowing bile. GallCleanse is the first natural therapy to put forward a mass of convincing research that shows exactly how these two problems can be reversed. Also, by coupling the flush with a monoterpene oil complex, GallCleanse offers a comprehensive approach to eliminating stones and resuming optimal health."
-- Dr. J. Pranay, Alternative Health Specialist, Pranay Center for Alternative Health

"As a physician I am always open to alternative ways of resolving health issues before opting for more drastic solutions. In the case of gallstones, I have found that the research on which the GallCleanse therapy has been based has significant promise. The 2 part approach of dissolving stones with a monoterpene complex then flushing the gallbladder and liver is indeed an effective way of finding relief from pain and eliminating the gallstone. Based on the safety of the GallCleanse ingredients, I recommend GallCleanse as an effective aid in natural gallstone therapy."
-- Dr. Ratan Vohra MBBS, St. Christopher Hospital

"In my clinical experience, GallCleanse is a remarkable breakthrough in natural gallstone therapy...By targeting the gallstone, gallbladder and liver at the same time, the problem is treated from all angles. The end result is a rapidly resolving state where the liver is able to produce better bile and the stone is able to shed its particles and be excreted."
-- Dr. Serrasa Tribhavan, Naturopath

These statements have not been evaluated by the food and drug administration. The products mentioned are not intended to diagnose, treat, cure or prevent any disease. Always see your licensed health care professional for proper diagnosis and treatment.

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