Hoodia has been used for thousands of years by the San Bushmen of the
Kalahari Desert to counter hunger and thirst on hunting trips. Hoodia has
been studied by many scientists the past few years to determine what
ingredients of hoodia are responsible for this effect on the appetite.
Most of the study has focused on an active ingredient called P57 which is
now believed to be the main active nutrient found in hoodia. In laboratory
animal test scientists discovered that animals with P57 injections
exhibited dramatic reductions of food intake.
Brown researchers believe that P57 is
active in the hypothalamus - a brain structure that controls numerous
drives in the body such as appetite, sex, sleep and mood. It is believed
that additional P57 is able to increase ATP (energy compound) levels. This
increase causes the hypothalamus to signal the brain the stop eating. P57
seems to work like just like glucose which is known boosts ATP levels and
reduces appetite. The difference is that P57 has no calories.
Many clinical studies are currently being
done to determine the effectiveness and safety of hoodia. The initial
results seem to indicate that hoodia could be a very valuable tool as an
Not all members of the Hoodia family of
plants are biologically active. Hoodia GL is produced from the species Hoodia
Gordonii which has been used in the food chain of the indigent desert
people of South Africa. It is very important that this species of Hoodia
be used in any supplement since the others may not have the same effect.
As a dietary supplement, adults
take one capsule with water, two times daily before meals, or as directed by a
health care professional. Store in a cool, dry place and away from direct
Keep out of reach of
children. Pregnant and nursing women should avoid taking Hoodia-GL